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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
14.24
Human Site:
S1655
Identified Species:
26.11
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
S1655
T
Y
E
N
T
D
E
S
T
N
S
S
S
V
W
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S1669
T
Y
E
N
T
D
E
S
T
N
S
S
S
V
W
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
S1655
T
Y
E
N
T
D
E
S
A
N
S
S
S
V
W
Dog
Lupus familis
XP_537704
2182
240593
S1663
T
Y
E
N
K
D
E
S
T
N
S
S
N
V
W
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
N1654
E
N
K
D
E
S
T
N
S
S
N
V
W
T
L
Rat
Rattus norvegicus
NP_001100505
2040
223488
K1548
Q
T
L
P
P
H
I
K
S
T
V
S
V
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
E1651
F
T
Y
E
N
K
D
E
S
T
N
S
N
I
W
Chicken
Gallus gallus
XP_415884
2225
244861
N1706
T
Y
E
K
K
D
E
N
S
S
S
S
S
L
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
Q1598
F
S
Y
E
E
N
C
Q
G
S
S
S
S
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
S2097
P
F
T
F
A
S
D
S
C
E
L
E
R
L
A
Honey Bee
Apis mellifera
XP_393643
1982
216109
K1490
G
R
A
R
E
R
R
K
I
Q
D
E
M
R
A
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
R2352
L
L
N
D
R
P
I
R
V
E
R
P
G
E
S
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
I635
Q
V
S
L
Q
R
N
I
A
F
Q
V
A
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
93.3
86.6
N.A.
0
6.6
N.A.
13.3
60
N.A.
33.3
N.A.
6.6
0
0
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
40
13.3
N.A.
46.6
86.6
N.A.
46.6
N.A.
26.6
0
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
16
0
0
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
0
39
16
0
0
0
8
0
0
0
0
% D
% Glu:
8
0
39
16
24
0
39
8
0
16
0
16
0
8
0
% E
% Phe:
16
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
16
8
8
0
0
0
0
8
8
% I
% Lys:
0
0
8
8
16
8
0
16
0
0
0
0
0
0
0
% K
% Leu:
8
8
8
8
0
0
0
0
0
0
8
0
0
16
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
8
31
8
8
8
16
0
31
16
0
16
8
0
% N
% Pro:
8
0
0
8
8
8
0
0
0
0
0
8
0
0
0
% P
% Gln:
16
0
0
0
8
0
0
8
0
8
8
0
0
8
0
% Q
% Arg:
0
8
0
8
8
16
8
8
0
0
8
0
8
8
0
% R
% Ser:
0
8
8
0
0
16
0
39
31
24
47
62
39
0
16
% S
% Thr:
39
16
8
0
24
0
8
0
24
16
0
0
0
8
0
% T
% Val:
0
8
0
0
0
0
0
0
8
0
8
16
8
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
54
% W
% Tyr:
0
39
16
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _